- Title
- Design of MDIs for type 1 diabetes treatment via rolling horizon cardinality-constrained optimisation
- Creator
- Carrasco, Diego S.; Matthews, Aaron D.; Goodwin, Graham C.; Delgado, Ramón A.; Medioli, Adrian M.
- Relation
- 20th IFAC World Congress. 20th IFAC World Congress: Toulouse, France, 9-14 July 2017: Proceedings [presented in IFAC-PapersOnLine, Vol. 50 Iss. 1] (Toulouse, France 9-14 July, 2017) p. 15044-15049
- Publisher Link
- http://dx.doi.org/10.1016/j.ifacol.2017.08.2516
- Publisher
- Elsevier
- Resource Type
- conference paper
- Date
- 2017
- Description
- Recent results on cardinality constrained optimisation are used to obtain an optimised Multiple Daily Injection (MDI) insulin regimen for Type 1 Diabetes patients. The optimisation is implemented in a rolling horizon fashion to account for unannounced events. A blood glucose model is described and an algorithm developed to illustrate the aforementioned strategy. The impact of varying the number of allowable injections in a given day is also studied. Real patient data is used to obtain the models and simulation results are included.
- Subject
- optimisation; diabetes; blood glucose regulation
- Identifier
- http://hdl.handle.net/1959.13/1385343
- Identifier
- uon:32209
- Identifier
- ISSN:2405-8963
- Language
- eng
- Full Text
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